Therapeutic Value Of Camel Milk Supplemented With Echinacea Consumption By Albino Rat

Ragaa Hosny Mohamad¹, Azza Mahmoud Farahat², Mohamad Gamil Abdel Moneim³, Amal Mohamad El-bastawesy⁴, Safaa Ahmed Salem⁵

¹Cancer Biology, National Cancer Institute,

²Food Science, Faculty of Agricultural, Ain Shams University

³,Surgical Oncology National Cancer Institute,

⁴Food Technology Research Institute, Agricultural Research Center, Egypt.

⁵Food Assurance, National Organization for Drug Control and Research.

Address correspondence to Correspondance:  Ragaa H.M.M. Al-Tahtawy,Ph.D

Division of Cancer Biology , National Cancer Institute-Cairo University. Fom Al-Khalig Street – Cairo Egypt -Post No: 11234.Tel: 00201001856864

Fax: 0020223644720; Email: ragaatahtawy@gmail.com ; ragaa.tahtawy@nci.cu.edu.eg

Accepted 15 March 2015

Abstract

This trial aims to clarify the role of the camel milk supplemented with three different ratio of the Echinacea and dates pulp on male albino rats fed on a high fat high cholesterol diet. The chemical content and GC-MS analysis for the Camel milk, dates pulp and   Echinacea had been determined.  Seventy male albino rats weight of 100±20 g. were divided randomly into seven  groups, ten rats in each. They were fed on standard diets and the camel milk supplemented with dates pulp and the Echinacea (1,3and5 %) respectively, for 60 days. By the end of the experimental period, all rats were anesthetized and sacrificed to obtain blood tissues samples. A significant difference in AST, ALT, GCT, ALB , TP,TB,ALP, CK, LDH TC, TG, glucose, α-amylase, GSH, MDA ,IgM, IgG, IL-2, IL-1α and IgE  levels were found between the  high fat high cholesterol group and others groups. Finally, the destructive changes in the cellular tissues of the liver and kidney had been stopped in all treated groups compared with the high fat high cholesterol group. In conclusion, the camel milk was successfully supplemented with different ratio of the Echinacea and dates pulp which is a functional food, with stimulating potential antioxidant effect. Finally, it had been stimulate necessary bioactive components, which play a great a role in stimulating the immune system effect. The improvement in the liver and kidney functions and other metabolic indicators, it might be reflected in stopping greatly the destructive changes in the cellular tissues of the liver and kidney.  

Keywords: aerial part of the Echinacea, date fruits, camel’s milk, Antioxidant activity, Immune  system.