Emergence of gram positive bacteria as a causal agents of spontaneous bacterial peritonitis.

Engy Yousry El sayed*, Eman Mohamoud Ezzat**, Rania Ali Amr***

*Ass. Prof. of Internal Medicine Department, Ain Shams University

** MD internal medicine

***Ass. Prof. Clinical pathology Faculty of Medicine, Ain Shams University

*Corresponding Author’s Email: ashorengy@yahoo.com

Accepted 02 May, 2014

Abstract

It has been suggested that the profile of spontaneous bacterial peritonitis has changed, and severe infections caused by resistant bacteria species have started to emerge. The aim of this work was to evaluate the recent changes in bacteria causing spontaneous bacterial peritonitis in cirrhotic patients. In this study, records of laboratory and ascitic fluid cultures data of 100 cirrhotic patients, with SBP, in the retrospective period from October 2007 to October 2008 and 120 patients with SBP in the prospective period from October 2011 to October 2012, were subjected to laboratory tests, ascitic fluid sent for bacterial culture along with routine biochemical and cytological examination were done. Results showed that the overall culture positivity rate was higher in prospective study period 39(32.5 %) versus retrospective period 35(35 %) p>0.05 and the main bacterial isolates were E. coli and Klebsiellapneumoniae. Gram positive bacteria (GPB) were isolated more frequently in the prospective than retrospective period 16 (41%) versus 10 (28.6%). Conclusion: There is an  emergence of Gram positive bacteria as a causal agents of SBP.

Keywords: Spontaneous bacterial peritonitis, gram-positive bacteria and infection.