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Vol. 2(2) February 2013
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Mishra M
Gautam RP
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Global Advanced
Research Journal of Microbiology (GARJM) ISSN: 2315-5116
February 2013 Vol.
2(2), pp 017-021
Copyright © 2013 Global Advanced
Research Journals
Full Length Research Paper
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Therapeutic
application of some chelating agents against
intoxication of Vanadium compounds in the
reproductive organs of male rats
Mahesh Mishra1,
R Mathur2 and R K Gautam3
1VISM,
Gwalior
2SOS
in Zoology, Jiwaji University, Gwalior
3School
of Life sciences, BRA University, Agra
*Corresponding Author’s E-mail:
fmishra.mishra@gmail.com
Accepted 25 January, 2013
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Abstract |
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Vanadium, an environmental pollutant and an element
commonly used in many industries is an established
toxicant in human being. It causes not only
physiological disturbances but also anatomical
changes in various parts of body including
reproductive organs. Vanadyl sulphate exposed rats
when treated with the 0.3 mmol/kg. b. wt. EDTA and
DTPA separately for four consecutive days recovered
fully. Their glycogen and protein content and
activity of acid phosphatase and alkaline
phosphatase become normal.In our study we found that
the chelators can be used as effective eliminators
of vanadium from the tissue and its toxic effects
can be alleviated.
Keywords: Acid phosphatase, alkaline
phosphatase, chelates, vanadium toxicity, apotosis
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