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February
2013 Volume 2 Issue 2
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Ogunlade JT
Egbunike GN
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Gobal Advanced Research Journal
of Environmental Science and Toxicology (GARJEST) ISSN:
2315-5140
February 2013 Vol. 2(2), pp.
047-053
Copyright © 2013 Global Advanced Research Journals
Full Length
Research Paper
Fumonisin mycotoxicity in laying hens: haematology, serum
biochemistry and organ characteristics
Ogunlade J. T.*1 and Egbunike G. N.2
1Department
of Animal Production and Health Sciences, Faculty of
Agricultural Sciences, Ekiti State University, Ado-Ekiti,
Nigeria
2Department
of Animal Science, Faculty of Agriculture and Forestry,
University of Ibadan, Nigeria
*Corresponding Author
Email:
taiwoogunlade2003@yahoo.com
Accepted 12 February, 2013
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Abstract |
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One hundred and twenty Isa-Brown Point-of-lay(POL)
birds were used in a sixteen(16) week dietary study
to evaluate the toxicity of fumonisin, an
environmental mycotoxin produced by fungi of the
genus Fusarium, on haematology, serum biochemistry
and organ characteristics. The POL birds were
divided into four groups with thirty birds per
group. Four nutritionally balanced test diets were
prepared to contain 0.2, 5.2, 10.2 and 15.2 ppm of
fumonisin B1 constituting diets 1
(control), 2, 3 and 4 respectively by substituting
ground corn cultured with F.moniliforme for
ground autoclaved, non-cultured corn in graded
proportions. Each group was assigned to one
experimental diet in a completely randomised design.
Blood and serum samples and some selected internal
organs were collected from the birds at the end of
the feeding trial for haematological, serum
biochemical and organs’ analyses. Results showed
that the erythrocytes, haemoglobin, packed cell
volume, mean corpuscular volume, mean corpuscular
haemoglobin concentration and leukocytes of birds
fed diets containing 5.2ppm, 10.2ppm and 15.2ppm FB1
were not significantly different (p>0.05) from those
fed the control (0.2ppm) diet. However, the mean
corpuscular haemoglobin and platelets of birds fed
the control (0.2ppm) diet were significantly
(p<0.05) higher than those fed diets 2, 3 and 4.
Experimental birds fed diets containing 5.2ppm FB1
and above suffered a significantly (p<0.05)
depressed syntheses of total protein, albumin,
aspartate aminotransferase (AST), uric acid and
albumin-globulin ratio. The relative weights of the
kidney, reproductive tract, lung and gastro
intestinal tract (GIT) were significantly (p<0.05)
lower in laying hens fed diets 3 and 4 than those
fed diet 1. This study demonstrated that dietary FB1
concentration above 5.2ppm is a potential health
risk that may induce adverse physiological response,
which can be assessed using serum biochemical
parameters and organs’ characteristics in laying
hens.
Keywords:
Isa-brown, autoclaved, non-cultured, physiological
response.
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