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February
2013 Volume 2 Issue 2
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Felemban HM
Al-Gehani SA
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Gobal Advanced Research Journal
of Environmental Science and Toxicology (GARJEST) ISSN:
2315-5140
February 2013 Vol. 2(2), pp.
054-059
Copyright © 2013 Global Advanced Research Journals
Full Length
Research Paper
Effect of organophosphate malathion on tissues of quail (Coturnix
coturnix)
Felemban H. M.1, Mujallid M. I.1 and
AL-Gehani S. A.1,2*
1Department
of Biology, King Abdulaziz University, B.O.Box: 80203
Jeddah, 21589, KSA.
2Department
of Biology, Taif University, B.O.Box: 21944, Taif, KSA
*Corresponding Author E-mail:
saj_vip.99@hotmail.com
Accepted 12 February, 2013
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Abstract |
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The aim of the present study to investigate effects
of the organophosphates insecticides malathion on
hematological and histopathological changes in liver
and illume tissues of quail (Coturnix
coturnix). Quail were treated orally with ¼ LD50
(25mg /kg B.W.) of malathion for 28 days.
Malathion decreased the body weight significantly at
the end of experimental. There were statistically
significantly decreased in hemoglobin content, and
increased the number of leucocytes in malathion
treated- quail as compared to control. There are
changes in the liver tissues as indicated by
cytoplasmic vaculation, congestion of liver portal
vein, infiltration inflammatory cells in many parts
of the hepatic lobe and increasing the number of
Kupffer cell. The histopathological changes in the
illume tissues
showed increased in
the size and number of goblet cells and
cytoplasmic vaculation on colummale epithelial cell.
We can conclude that the malathion induced toxicity
in some blood parameters and caused
histopathological changes in the liver and illume of
quail.
Keywords:
Organophosphates insecticides, Malathion,
Histopathological changes, Coturnix
coturnix.
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