Study of C- peptide and glycoslated hemoglobin in obese and obese with type 2 diabetes and its relation with lipid profile from Sohag Governarate-Egypt

Elsawi  N. M.^1,*, Omar  H. M.², Hassan A. A.³ and Ahmed A. M.¹

¹Chemistry Department, Faculty of Sience, Sohage University, Sohage 82524, Egypt

²Zoology Department, Faculty of Science, Assiut University, Assiut 71516, Egypt

³Internal Medicine Department, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.

*Corresponding Author E-mail: elsawinagwa@yahoo.com 

Accepted 15 December, 2014

Abstract

Individuals with coexisting diabetes and metabolic syndrome have the highest prevalence of lipid abnormalities and cardiovascular disease. The aim of this study give attention for the risk associated with the increase of obesity rates and its complications in Egypt. This study was conducted on 91 subjects at Hospital of Sohag University to evaluate the relationship between levels of HbA1C, c-peptide and lipid profile in obese and obese diabetic patients.  The results showed that both obese and obese diabetic subject has higher blood pressure, blood glucose, HbA1C, C-peptide, total cholesterol, TG, LDL-C and lower HDL than normal control subjects. In addition, the previous parameters were higher in diabetic obese than normal obese subject. It is concluded that these results suggest that HbA1c, C-peptide level can be used as tools for predicting the lipid profile of both normal obese and obese diabetic patients. Glycated hemoglobin (HbA1C) is the indicator of glycamic status over long term. C-peptide is inflammatory markers elevated in diabetic patients.

Keywords: HbA1c, C-peptide, lipid profile, obese, diabetes.