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September 2012 Vol. 1 Issue
8
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Shugaba AI
Hambolu JO
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Global Advanced Research Journal
of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
September 2012 Vol. 1(8), pp.
203-207
Copyright © 2012 Global Advanced
Research Journals
Full Length Research Paper
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White blood cells` response of female wistar rats
following induced physical and oxidative stress
A.I. Shugaba1*, S. A. Ojo2,
A.S. Asala3, A.M. Rabiu4, C.B.
Uzokwe1 and J.O. Hambolu2
1Department
of anatomy, faculty of medical sciences, university
of Jos, Nigeria.
2Department
of vetinary anatomy, faculty of vetinary medicine,
A.B.U. Zaria, Nigeria.
3Department
of anatomy, college of health sciences, university
of Abuja, Nigeria.
4Department
of physiology, faculty of medical sciences,
university of Jos, Nigeria.
*Corresponding author E-mail:
alishugaba@yahoo.com
Accepted 16 August, 2012
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Abstract |
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The effect of induced physical and oxidative stress
on the white blood cells (WBC) of female Wistar rats
was investigated. 40 matured female Wistar rats were
divided into four groups (A.B.C.D) ten per group.
Group A, control, Group B, mono enucleation, Group
C, bilateral enucleation and Group D, alcohol
treated. The total and differential white cell
counts were evaluated over the six weeks period of
the induced stress. The results revealed no
difference in the average total and differential
white cell counts of the mono and bilaterally
enucleated groups. While the alcohol treated group
showed increase especially in the total WBC,
neutrophils and eosinophils compared to the control
group (P-value <0.05).
Keywords:
Induced stress, Female Wistar rats, White blood
cells (WBC).
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